This book gathers a collection of high-quality peer-reviewed research papers presented at the 4th International Conference on Data and Information Sciences (ICDIS 2022), held at Raja Balwant Singh Engineering Technical Campus, Agra, India, on May 6 - 7, 2022. The book covers all aspects of computational sciences and information security, including central topics like artificial intelligence, cloud computing, and big data. Highlighting the latest developments and technical solutions, it will show readers from the computer industry how to capitalize on key advances in next-generation computer and communication technology.