One of the fundamental aspects of the cultural landscape of the last century has been the revival of philosophical anthropology, in the form of a radical examination of the humanum: an examination that has attempted to meet the primary challenge of an era which, in an increasingly radical way, doubts the very possibility of a semantics of humanism. This book argues that MacIntyrean thought can provide an important contribution towards rethinking a new semantics of humanism, on the basis that MacIntyre’s contribution stands up to dialogue with and rational competition from perspectives belonging to rival research traditions. The volume emerged from the 2021 conference at the University of Bergamo, in collaboration with the International Society for MacIntyrean Enquiry.