The Role of Cytokines in Periodontology

This book explores the pivotal role of cytokines in periodontal health, disease, and healing. Cytokines are small signaling proteins that regulate cellular communication, immune responses, and tissue remodeling. In health, they maintain homeostasis by coordinating cell growth, differentiation, and matrix synthesis. In inflammation, cytokines like IL-1, IL-6, TNF-?, and IL-17 contribute to tissue destruction and bone resorption. The book discusses their mechanisms, receptors, classification, and involvement in immune modulation, chemotaxis, and wound healing. It also highlights anti-inflammatory cytokines such as IL-10 and TGF-? in repair processes, and examines cytokine storms and their systemic implications. Therapeutic strategies targeting cytokines are explored as potential adjuncts in periodontal treatment. With extensive literature support, this book provides a comprehensive understanding of cytokines as key mediators in periodontology.