Psychedelics modulate brain function leading to an adult onset cerebellar cognitive affective disorder with an anarchic brain- anti-authoritarian environmentally conscious brain- required to fight climate change. Endosymbiotic archaea can synthesize ethyl alcohol from carbohydrates leading to endogenous alcohol synthesis and cerebellar cognitive affective disorder. Extinction rebellion and psychedelics can be related to endogenous archaeal related tyrosine and tryptophan alkaloidal like LSD synthesis. The aromatic amino acids L-tryptophan and L-tyrosine are the most important in this respect. L-tryptophan is the precursor of not only serotonin, a well known neurotransmitter, but also of two other neuroactive substances, quinolinic acid and kunurenic acid. L-tyrosine is the precursor of dopamine and other catecholamines. Morphine, an alkaloidal neurotransmitter, is synthesized from tyrosine. Recently the presence of endogenous strychnine and nicotine has been reported in the brain of rats loaded with tryptophan. The archaeaons which are endosymbiotic archaea can form neurotransminoids with the shikimic acid pathway generating neuroactive alkaloids.