Chromatin Remodelling

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The book provides an introduction and comprehensive information regarding chromatin remodelling. Chromatin remodelling is used to describe the dynamic modification of chromatin architecture governed by histone-modifying enzymes, non-histone DNA-binding proteins, chromatin remodelling complexes and noncoding RNAs. Various diseases and disorders such as cancer, autism etc. have been related to the breakdown of these control mechanisms by genetic, environmental or microbial factors. The mechanisms through which these factors work are evolving as a new and interesting genre of research and would help in discovering new ways of treatments of these diseases. This book covers recent developments in the domain of biology dealing with gene regulation, chromatin structure, DNA recovery and human diseases.