In the ultimate war of man vs. machine, the fate of humanity lies with a teenage cyborg named Shio! Living in constant fear of attack from machines, mankind depends on the cyborg corps known as the Guardians to keep them from harm as they await the arrival of the Kami, a godlike savior with mythical red blood who can grant only one wish to one person. Now, Shio, son of a Guardian, thinks he’s found the Kami–and all the Guardians are at war to get that wish!

The girl who could be the Kami is kidnapped by a trio of mysterious sages. To save her, Shio must join forces with a former opponent and battle through a slew of ever-more-powerful renegade Guardians!