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This book covers fundamentals, experimental details, and applications of the technologies that enable high throughput mass spectrometry-based screens in supporting drug discovery. These include hit discovery by label-free screening, synthetic reaction optimization, lead optimization and SAR support, and other ADME (absorption, distribution, metabolism, and excretion) - Toxicology screening.
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This book covers fundamentals, experimental details, and applications of the technologies that enable high throughput mass spectrometry-based screens in supporting drug discovery. These include hit discovery by label-free screening, synthetic reaction optimization, lead optimization and SAR support, and other ADME (absorption, distribution, metabolism, and excretion) - Toxicology screening.