This comprehensive and authoritative text summarizes current evidence and provides experienced perspectives on the etiology, diagnosis, and management of pediatric thrombotic disorders, including arterial ischemic stroke and cerebral sinovenous thrombosis. Authored by leaders in the field, individual chapters are devoted to specific anatomic sites and types of thrombosis. State-of-the-art, pediatric-focused chapters aid in diagnostic evaluation and therapeutic decision making, in settings ranging from the most routine to the most complex and challenging patient scenarios. Topics include: extremity and caval deep venous thrombosis; pulmonary embolism; cancer-associated thromboembolism; infection-associated thromboembolism; arterial ischemic stroke; cerebral sinovenous thrombosis; gastrointestinal and visceral thrombosis; developmental hemostasis; thrombophilias; heparin-induced thrombocytopenia/thrombosis syndrome; venous thromboembolism prevention; thrombolysis; and novel anticoagulants, among others. This text is a ‘must-have’ for practitioners in pediatric hematology, oncology, hematopoietic stem cell transplantation, neurology, hospital medicine, and intensive care.