Orlistat Easy Guide Book Orlistat is adjudged the safest weight loss pill in the market as not even a percent of it is absorbed by the blood stream even in a long term use. Orlistat has good tolerance level with predictable and manageable side effects. However, one is expected to arm one’s self with the prerequisite knowledge before consumption of Orlistat. John Cook’s Orlistat Easy Guide Book is one book that explains the many grey areas concerning the use of Orlistat in vivid terms.