Imaging Drug Action in the Brain

This reference provides detailed methodological information and presents a current review of information obtained using various methods to delineate the neuroanatomy of drug action. In vivo metabolic mapping studies delineate the distributions of action of psychoactive drugs in animals, and material is provided which covers selective lesioning and intracranial injections in intact animals. This book presents recent advances in extending these types of studies to human investigations, using positron emission tomography (PET) scanning and elctrophysiological imaging techniques. The book discusses various applications of receptor binding techniques and their importance in pharmacology, and explains applications of immunocytochemical and molecular biology techniques in studies of drug action. It provides up-to-date examples of the applications of technique. The book is aimed at neuropharmacologists, neuroanatomists, neurophysiologists, and nulcear medicine specialists,and radiologists.