Pathophysiology of Heart Failure

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This volume brings together leading basic scientists and clinicians, presenting new approaches to the complex problem of heart failure, involving cardiomyopathic processes and ischemia perfusion injury. The result is a synthesis of information on molecular biology, cellular physiology and structure-function relationships in the cardiovascular system. The role which excess intracellular calcium plays in the genesis of cardiac dysfunction is described as a fundamental mechanism underlying heart failure; one which may lead to improved prevention and treatment. This book is intended for clinical and experimental cardiologists.