This study makes a methodological effort to advance the social science debate on post-communist transformation beyond the limitations of its first decade. Offering theoretical and empirical analyses of fundamental economic, cultural and political problems of systemic change and reform in Central and Eastern Europe, the authors seek to broaden and deepen the research agenda by developing a set of interrelated approaches that are cross-disciplinary, sociologically informed, historically comparative, and global. The work’s major substantive themes revolve around problems of post-communist socio-economic transformations. Specifically, it explores post-communist systemic change, the role of religion and collective identity, the significance of trust and economic culture, patterns of state-economy interactions in enterprise restructuring, the context of EU expansion, the strengths and weaknesses of economic theory and neo-liberal doctrine, and the history of ideas in the post-communist transformation debate.