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Lipids are the cell's hydrophobic metabolites, and their self-assembly into bilayers creates membranes that are critical barriers and organizing platforms in cells. Lipids are a chemically diverse set of biological molecules subject to rapid metabolism and transport, and this dynamic behavior has motivated the development of methods across multiple disciplines for their detection and manipulation. Split into three parts, the Volumes on Lipids and Membranes provide a broad snapshot of the state of the art of methods for studying biological lipids and biomembranes. This part focuses on approaches for tracking the metabolic interconversions of lipids, including the posttranslational modification of proteins with lipids (lipidation) as well as non-covalent lipid-protein interactions.
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Lipids are the cell's hydrophobic metabolites, and their self-assembly into bilayers creates membranes that are critical barriers and organizing platforms in cells. Lipids are a chemically diverse set of biological molecules subject to rapid metabolism and transport, and this dynamic behavior has motivated the development of methods across multiple disciplines for their detection and manipulation. Split into three parts, the Volumes on Lipids and Membranes provide a broad snapshot of the state of the art of methods for studying biological lipids and biomembranes. This part focuses on approaches for tracking the metabolic interconversions of lipids, including the posttranslational modification of proteins with lipids (lipidation) as well as non-covalent lipid-protein interactions.