Much research has been done in the field of skin metabolism and how this can be adversely affected by xenobiotics which we come into contact with routinely. This book collates, reviews and discusses these advances within one comprehensive source. It reviews current knowledge of percutaneous absorption, skin metabolism and the skin’s immune system. In addition it will discuss the xenobiotics themselves - how allergenic they are and how we can predict safe levels in food, cosmetics and pharmaceuticals. Researchers in academia, government, regulatory bodies, public health officials and, of course, the food, cosmetics and pharmaceuticals industries will find this one stop reference the most up to date and comprehensive in a field that is becoming increasingly important every year. Smith; Camilla Levers Brothers, UK,Hotchkiss; Sharon Imperial College of Medicine, England, UK,