Drug Delivery to the Lung

This book focuses on the aerosol treatment of lung diseases, recent improvements in the understanding of proper dosage, and major innovations in device technology applied to clinical practice.

Examines the behavior of inspired spherical particles in the respiratory tract!

Featuring over 1300 references, drawings, tables, photographs, and micrographs, Drug Delivery to the Lung

outlines the history of inhaled medications in the treatment of respiratory disease

describes aspects of respiratory structure to inhalation therapy emphasizing developmental changes

compares existing in vitro/in vivo correlations for key aerosol modalities with lung model predictions

discusses particle diameter measurement, particle size statistics, and aerosol test methods

reviews the clinical effects of altering the deposition site of various classes of aerosolized drugs

surveys the development of novel, efficient, and convenient nebulizer systems

details breath-actuated and spacer devices constructed for children

analyzes dry-powder and pressurized metered dose inhalers

considers the transition from CFCs to new environmentally friendly chemical propellants

and more! Giving the clinician an overview of factors essential to understanding drug delivery via nebulization, Drug Delivery to the Lung is a superlative reference for pulmonologists; physiologists; pharmaceutical scientists; immunologists; allergists; analytical, organic, and medicinal chemists and biochemists; chemical, genetic, and process engineers; and medical and graduate school students in these disciplines.