The curve of Spee exists in natural dentition allows harmony among anterior teeth, posterior teeth and condylar path. This anteroposterior curve is introduced in complete denture prosthesis to achieve balanced occlusion. The Curve of Spee emerges as a key player in facilitating protrusive disocclusion, preventing interferences, optimizing masticatory force distribution, and ensuring balanced occlusion. Understanding and managing this curvature is crucial for achieving optimal outcomes in complete dentures and full mouth rehabilitations. Understanding and managing the Curve of Spee is crucial for achieving optimal occlusal function in prosthodontics. Future research should explore individual variability, interactions with other occlusal factors, and advanced measurement and incorporation techniques.