Gray’s Anatomy, published in the UK in 1858 under the original title Anatomy: Descriptive and Surgical, is a detailed English textbook on human anatomy, focused on teaching medical students human anatomy for practical knowledge during surgery. This unique first edition includes more than 300 pages of illustrations by H.V. Carter, M.D. Each image is labeled with the corresponding bones, muscles, nerves, and organs. In addition, the book is separated into chapters based on the systems of the body for easy use. While Gray’s Anatomy may no longer be a suitable study guide for modern physicians, it is considered a classic work on the subject and is a great reference for those interested in the origins of the study of human anatomy. HENRY GRAY (1827-1861) was a renowned British anatomist who studied at St George’s Hospital Medical School in London. His focus was on the endocrine glands and spleen until he approached fellow colleague Henry Vandyke Carter to help him write a comprehensive and accessible anatomy textbook. The team worked for more than a year studying unclaimed cadavers to help write the text. It was published in England in 1858 and in America only one year later. Gray published the first two editions before it was acquired by Longman’s in 1863, shortly after Gray’s early death from smallpox.