Brute Greenbaum faces challenges beyond those of ordinary 12-year-olds. Faded hearing. Dimming eyesight. Bad hips. A penchant for farting. They're normal for an English Bulldog equivalent to a human centenarian and pursued by the "Malach HaMavet"-the Angel of Death. But they're only the beginning. A cantankerous lover of literature, rabinnic wisdom, humor and skateboarding, Brute must hold together the remnants of his shattered San Francisco family. Abbie Greenbaum, a 24-year-old dog walker, remains estranged from his college-professor father Morty more than a decade after the deaths of Abbie's sister and mother. Yet he and Morty still live in the same house. Enter Sarah-a 10-year-old with Down syndrome-and Rivka, her divorced Jewish-Chinese mother who teaches stand-up comedy and can't shake her ex, a classically trained cellist into bondage. The three Greenbaums encounter a series of trials posed by mortality, jealousy and long-buried secrets, which represent nothing-and "everything"-to laugh about.