Evelyn Fox Keller trained as a theoretical physicist at a time when women didn't "do physics." Unable to find a supportive advisor, she moved into the new field of molecular biology just getting off the ground. After receiving her doctorate, she returned to physics but then took another swerve, joining a small interdisciplinary effort to develop mathematical models of biological systems. This work led to her appointment to a special position as Professor of Mathematics and Humanities at Northeastern University. When second-wave feminism arrived in the 1960s, it changed the lives of everyone in its path. It certainly changed Keller's, leading her beyond the borders of science altogether. Eventually she began to think of herself as a dual citizen of the proverbial two cultures--science and humanities. The trajectory was hardly straightforward, nor was it conducive to building a conventional career, or even getting a job. Now in hindsight, after an illustrious career and having published fourteen books, Keller reflects on her life, influences, successes and struggles along her trailblazing path as a scientist and feminist.