In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish interventions that are beneficial, are superior to all alternatives and are cost-effective. Usually one study will not provide answers to these questions and it will be necessary to synthesize evidence from multiple sources. This book aims to outline a coherent approach to such evidence synthesis, for the purpose of decision making. Each chapter contains worked examples, exercises and solutions drawn from a variety of medical disciplines Evidence Syntesis for Decision Making intends to provide a practical guide to the appropriate methods for synthesizing evidence for use in analytical decision models. More specifically, it proposes a comprehensive evidence synthesis framework, which models all the available data appropriately and efficiently in a format that can be incorporated directly into a decision model.